(3β)-16-[(3β)-3-Hydroxyandrosta-5,16-dien-17-yl]-17-(3-pyridinyl)-androsta-5,16-dien-3-ol
| Product Name |
(3β)-16-[(3β)-3-Hydroxyandrosta-5,16-dien-17-yl]-17-(3-pyridinyl)-androsta-5,16-dien-3-ol
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| Product Code |
H0000124
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| Chemical name |
(3β)-16-[(3β)-3-Hydroxyandrosta-5,16-dien-17-yl]-17-(3-pyridinyl)-androsta-5,16-dien-3-ol
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| Synonyms |
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| Impurity |
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| CAS Number |
186826-70-0
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| Alternate CAS # |
NA
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| Molecular form |
C₄₃H₅₇NO₂
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| Appearance |
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| Melting Point |
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| Mol. Weight |
619.92
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| Storage |
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| Solubility |
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| Stability |
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| Category |
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| Boiling Point |
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| Applications |
(3β)-16-[(3β)-3-Hydroxyandrosta-5,16-dien-17-yl]-17-(3-pyridinyl)-androsta-5,16-dien-3-ol is a derivative of Abiraterone (A108490), which is a steroidal cytochrome P 450 17α-hydroxylase-17,20-lyase inhibitor (CYP17), is currently undergoing phase II clinical trials as a potential drug for the treatment of androgen-dependent prostate cancer.
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| Dangerous Goods Info |
NA
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| References |
Denis, L., et al.: Cancer, 72, 3888 (1993), Potter, G.A., et al.: J. Med. Chem., 38, 2463 (1995), Denmeade, S., et al.: Nat. Rev., 2, 389(2002), Scher, H., et al.: J. Clin. Oncol., 23, 8253 (2005),
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| Extra Notes |
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| Documents (MSDS) |
No Data Available
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| Keywords |
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